SCHEMBL922282

SCHEMBL922282

CCOCCCCOc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.55
LMNA P02545 4/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
FAAH O00519 1/20 0.47
EGLN1 Q9GZT9 1/20 0.46
MAPK8 P45983 1/20 0.46
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920417 0.94 LMNA (0.56) HPGDLMNASMN1; SMN2FAAHEGLN1
SCHEMBL922835 0.91 LMNA (0.56) HPGDLMNASMN1; SMN2FAAHEGLN1
SCHEMBL920132 0.91 LMNA (0.58) HPGDLMNASMN1; SMN2FAAHEGLN1
SCHEMBL920970 0.90 LMNA (0.55) HPGDLMNASMN1; SMN2FAAHTSHR
SCHEMBL921855 0.89 HPGD (0.55) HPGDLMNASMN1; SMN2FAAHEGLN1
SCHEMBL923598 0.89 HPGD (0.55) HPGDLMNASMN1; SMN2FAAHEGLN1
SCHEMBL921293 0.89 HPGD (0.55) HPGDLMNASMN1; SMN2FAAHEGLN1
SCHEMBL920353 0.89 LMNA (0.65) HPGDLMNASMN1; SMN2EGLN1MAPK8
SCHEMBL920921 0.89 HPGD (0.58) HPGDLMNASMN1; SMN2MAPK8KMT2A
SCHEMBL922146 0.88 LMNA (0.55) HPGDLMNASMN1; SMN2FAAHEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.