Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299882 | 0.89 | ALDH1A1 (0.50) | HPGDHTTRAB9AMAPTTSHR | |
| SCHEMBL2744596 | 0.87 | RAB9A (0.44) | HTTRAB9ATSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28078944 | 0.85 | RAB9A (0.42) | HTTRAB9ATSHRSMN1; SMN2LMNA | |
| SCHEMBL29024369 | 0.81 | HPGD (0.52) | HPGDCA12CA9HTTNPC1 | |
| SCHEMBL2326152 | 0.79 | HPGD (0.50) | HPGDCA12CA9HTTNPC1 | |
| SCHEMBL9571711 | 0.79 | CYP1A2 (0.47) | HPGDHTTNPC1RAB9AMAPT | |
| Acetic Acid SCHEMBL28853221 | 0.78 | RAB9A (0.50) | HTTNPC1RAB9AMAPTTSHR | |
| Acetic Acid SCHEMBL28078963 | 0.78 | RAB9A (0.50) | HTTNPC1RAB9AMAPTTSHR | |
| SCHEMBL21396206 | 0.74 | MAPT (0.48) | HTTNPC1RAB9AMAPTTSHR | |
| SCHEMBL28494839 | 0.73 | HPGD (0.64) | HPGDHTTNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304239-B1 | Reformed polysilazane and method of producing same | TOA NENRYO KOGYO KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-4975512-A | Crosslinking with amine, ammonium, hydrazine | PETROLEUM ENERGY CENTER (JP) | 1990-12-04 | — | — | US | disclosed |