Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151430 | 1.00 | CCR1 (0.42) | CCR1CCR5CCR8ENPP2PLG | |
| SCHEMBL3873666 | 0.88 | KDM4E (0.54) | CCR1CCR5CCR8CA1CA2 | |
| SCHEMBL29955214 | 0.83 | ASIC3 (0.53) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL21527865 | 0.83 | ASIC3 (0.53) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL24610115 | 0.83 | PLG (0.33) | CCR1CCR5CCR8ENPP2PLG | |
| SCHEMBL25224336 | 0.82 | JMJD6 (0.56) | CCR1CCR5CCR8KDM4E | |
| SCHEMBL31333872 | 0.80 | NPC1 (0.44) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL15332828 | 0.80 | NPC1 (0.44) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL29950674 | 0.79 | IDO1 (0.46) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL29953273 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7133283-A | — | — | None | — | — | JP | disclosed |
| JP-H07133283-A | AROMATIC BETA-DIMINE-BASED COMPOUND | RES DEV CORP OF JAPAN | 1995-05-23 | — | — | JP | disclosed |