Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332828 | 1.00 | NPC1 (0.44) | NPC1MEN1RAB9AKMT2AATM | |
| SCHEMBL29955214 | 0.81 | ASIC3 (0.53) | NPC1RAB9ATGFBR1PLGF12 | |
| SCHEMBL21527865 | 0.81 | ASIC3 (0.53) | NPC1RAB9ATGFBR1PLGF12 | |
| SCHEMBL9224607 | 0.80 | CCR1 (0.42) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL30151430 | 0.80 | CCR1 (0.42) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL21375941 | 0.78 | ADORA3 (0.38) | NPC1RAB9APLGF12F11 | |
| SCHEMBL2554661 | 0.78 | ENPP2 (0.52) | NPC1MEN1RAB9AKMT2ATGFBR1 | |
| SCHEMBL20158887 | 0.76 | ENPP2 (0.54) | TGFBR1 | |
| SCHEMBL27157236 | 0.76 | NPC1 (0.56) | NPC1MEN1RAB9AKMT2AATM | |
| SCHEMBL29950674 | 0.74 | IDO1 (0.46) | MAPKAPK2PLGF12F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |