Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209959 | 0.79 | FGFR4 (0.35) | ALDH1A1TDP1HPGDCYP3A4ALOX15 | |
| SCHEMBL9222293 | 0.76 | NPBWR1 (0.37) | ALDH1A1TDP1MAPTNPBWR1SMN1; SMN2 | |
| SCHEMBL9217796 | 0.75 | NPBWR1 (0.36) | ALDH1A1TDP1NPBWR1SMN1; SMN2CBFB | |
| SCHEMBL9217719 | 0.75 | NPBWR1 (0.36) | ALDH1A1HPGDNPBWR1SMN1; SMN2NPC1 | |
| SCHEMBL9217849 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TDP1HPGDCYP3A4ALOX15 | |
| SCHEMBL9222300 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TDP1HPGDCYP3A4ALOX15 | |
| SCHEMBL9222229 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TDP1HPGDCYP3A4ALOX15 | |
| SCHEMBL28920099 | 0.73 | ALDH1A1 (0.33) | ALDH1A1TDP1CYP3A4MAPTNPBWR1 | |
| SCHEMBL10774797 | 0.70 | TDP1 (0.51) | ALDH1A1TDP1HPGDCYP3A4ALOX15 | |
| SCHEMBL10108156 | 0.69 | MAPT (0.38) | ALDH1A1TDP1HPGDCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380865-A | Halogen substituents | MAY & BAKER LIMITED (GB) | 1995-01-10 | — | — | US | disclosed |
| US-5206257-A | Controlling plant nematodes, helminth, protozoa | MAY & BAKER LIMITED (GB) | 1993-04-27 | — | — | US | disclosed |
| EP-0283173-A1 | Pesticidal method using 2-phenylimidazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |