SCHEMBL9217796

SCHEMBL9217796

FC(F)(F)c1cc(Cl)c(-c2nc(Br)c[nH]2)c(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 3/20 0.36
CBFB Q13951 1/20 0.35
KIF20B Q96Q89 1/20 0.33
GABRA2 P47869 3/20 0.33
GABRB2 P47870 3/20 0.33
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33
GABRG3 Q99928 2/20 0.33
GABRQ Q9UN88 2/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9222293 0.82 NPBWR1 (0.37) NPBWR1CBFBKIF20BGABRA2GABRB2
SCHEMBL9217719 0.81 NPBWR1 (0.36) NPBWR1CBFBKIF20BGABRA2GABRB2
SCHEMBL9224699 0.75 ALDH1A1 (0.43) NPBWR1CBFBALDH1A1SMN1; SMN2TDP1
SCHEMBL9218751 0.74 NPBWR1 (0.39) NPBWR1CBFBGABRA2GABRB2GABRP
SCHEMBL9217797 0.73 NPBWR1 (0.38) NPBWR1CBFBGABRA2GABRB2GABRP
SCHEMBL9217753 0.70 MRGPRX4 (0.47) NPBWR1CBFBKIF20BGABRA2GABRB2
SCHEMBL9218118 0.69 NPBWR1 (0.37) NPBWR1CBFBGABRA2GABRB2GABRP
SCHEMBL9704101 0.69 NPBWR1 (0.38) NPBWR1CBFBALDH1A1TDP1
SCHEMBL9668609 0.68 HPGD (0.31)
SCHEMBL9223795 0.68 NPBWR1 (0.39) NPBWR1CBFBGABRA2GABRB2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380865-A Halogen substituents MAY & BAKER LIMITED (GB) 1995-01-10 US disclosed
CN-1024887-C 2-phenylimidazole derivative-containing pesticide MAY & BAKER LTD (GB) 1994-06-08 CN disclosed
US-5206257-A Controlling plant nematodes, helminth, protozoa MAY & BAKER LIMITED (GB) 1993-04-27 US disclosed
CN-1030577-A Disinsection method with 2-phenylimidazole derivative MAY & BAKER CO LTD (GB) 1989-01-25 CN disclosed
EP-0283173-A1 Pesticidal method using 2-phenylimidazole derivatives RHONE-POULENC AGRICULTURE LIMITED (GB) 1988-09-21 EP disclosed