SCHEMBL9224796

SCHEMBL9224796

CCCN(Cc1ccc2nc(-c3ccccc3C(=O)O)ccc2c1)c1ncccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 20/20 0.55
AGTR2 P50052 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569237 0.78 AGTR1 (0.69) AGTR1AGTR2
SCHEMBL8929477 0.77 RAB9A (0.44)
SCHEMBL9589791 0.76 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL9229489 0.75 PDE7A (0.46)
SCHEMBL8807794 0.74 LTB4R2 (0.47) AGTR1
SCHEMBL8807800 0.74 LTB4R2 (0.50) AGTR1
SCHEMBL9292766 0.73 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL8485364 0.73 LTB4R2 (0.48) AGTR1
SCHEMBL7300746 0.73 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL8487982 0.72 LTB4R2 (0.44) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7238071-A None JP disclosed
JP-H07238071-A NEW QUINOLINE DERIVATIVE HAVING SUBSTITUTED AMINO GROUP ASAHI GLASS CO LTD 1995-09-12 JP disclosed