Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8929477 | 0.88 | RAB9A (0.44) | PDE7APDE7BRAB9ANPC1LTB4R2 | |
| SCHEMBL8322442 | 0.81 | KDM4E (0.55) | RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL5106250 | 0.79 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8326990 | 0.77 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8807794 | 0.77 | LTB4R2 (0.47) | PDE7APDE7BLTB4R2BRS3 | |
| SCHEMBL9224796 | 0.75 | AGTR1 (0.55) | — | |
| SCHEMBL8807800 | 0.74 | LTB4R2 (0.50) | PDE7APDE7BLTB4R2 | |
| SCHEMBL8807157 | 0.74 | LTB4R2 (0.39) | PDE7APDE7BLTB4R2LPAR1BRS3 | |
| SCHEMBL5151244 | 0.74 | LTB4R2 (0.60) | LTB4R2FOLH1LPAR1BRS3 | |
| SCHEMBL8809185 | 0.74 | ALDH1A1 (0.43) | PDE7APDE7BLTB4R2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632027-A1 | 6-(Carbonyloxymethylene)-quinolines | BASF Aktiengesellschaft (DE) | 1995-01-04 | — | — | EP | disclosed |