Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 5/20 | 0.64 |
| ▸ | ACHE | P22303 | 5/20 | 0.56 |
| ▸ | BACE1 | P56817 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825827 | 0.89 | PDGFRB (0.68) | PDGFRBACHEBACE1MAPT | |
| SCHEMBL8825610 | 0.86 | PDGFRB (0.61) | PDGFRBACHEBACE1MEN1KMT2A | |
| SCHEMBL7473621 | 0.84 | PDGFRB (0.60) | PDGFRBACHEBACE1MEN1KMT2A | |
| SCHEMBL8796541 | 0.84 | EGFR (0.47) | PDGFRBACHELMNAMAPT | |
| SCHEMBL2918889 | 0.84 | PDGFRB (0.75) | PDGFRB | |
| SCHEMBL8825751 | 0.83 | CYP1A2 (0.55) | PDGFRBACHEBACE1MEN1KMT2A | |
| SCHEMBL8825752 | 0.83 | PDGFRB (0.60) | PDGFRBACHEBACE1MEN1KMT2A | |
| SCHEMBL2920292 | 0.81 | PDGFRB (0.59) | PDGFRBACHEBACE1LMNAMAPT | |
| SCHEMBL8825785 | 0.81 | PDGFRB (0.58) | PDGFRBACHEBACE1MAPT | |
| SCHEMBL8825745 | 0.81 | PDGFRB (0.46) | PDGFRBACHEBACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668280-A1 | IMIDAZOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |