Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 14/20 | 0.47 |
| ▸ | MAOA | P21397 | 14/20 | 0.47 |
| ▸ | MAOB | P27338 | 14/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679608 | 0.84 | MAOA (0.43) | KDM1AMAOAMAOBKDM4EGAA | |
| SCHEMBL21847487 | 0.80 | MAOA (0.32) | KDM1AMAOAMAOB | |
| SCHEMBL8734945 | 0.71 | MAPT (0.34) | KDM1AMAOAMAOBKDM4EGAA | |
| SCHEMBL1432099 | 0.70 | MAPT (0.33) | KDM1AMAOAMAOBKDM4EGAA | |
| SCHEMBL3223717 | 0.69 | CYP1A2 (0.42) | KDM1AMAOAMAOBKDM4EGAA | |
| SCHEMBL9250732 | 0.69 | CYP1A2 (0.42) | KDM1AMAOAMAOBKDM4EGAA | |
| SCHEMBL23465403 | 0.64 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15767313 | 0.64 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL10375585 | 0.64 | ALDH1A1 (0.50) | KDM1AMAOAMAOBKDM4EGAA | |
| SCHEMBL15541945 | 0.64 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447916-A | Hypotensive agents | CHIRON CORPORATION (US) | 1995-09-05 | — | — | US | disclosed |