Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223165 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL25142829 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL31267447 | 0.74 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| Hydrochloric Acid SCHEMBL9226874 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL5320191 | 0.72 | NPC1 (0.67) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL9224574 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL2061977 | 0.72 | ALDH1A1 (0.69) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL866062 | 0.71 | ALDH1A1 (0.64) | ALDH1A1HPGDHSD17B10TP53MAPK1 | |
| SCHEMBL10675512 | 0.70 | SMN1; SMN2 (0.59) | ALDH1A1HPGDSMN1; SMN2LMNAMEN1 | |
| SCHEMBL9229356 | 0.70 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |