Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188551 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2HSD17B10NAMPT | |
| SCHEMBL17383408 | 0.81 | GAA (0.58) | ALDH1A1KDM4ESMN1; SMN2NAMPTNPC1 | |
| Hydrochloric Acid SCHEMBL9220360 | 0.78 | MAPT (0.42) | ALDH1A1SMN1; SMN2NAMPTPBKGAA | |
| SCHEMBL11727549 | 0.78 | NPC1 (0.59) | ALDH1A1HPGDHSD17B10NAMPTPTGS2 | |
| SCHEMBL9224980 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL9228612 | 0.77 | KMT2A (0.55) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL9223763 | 0.77 | PPARG (0.60) | ALDH1A1KDM4EHPGDLMNANAMPT | |
| SCHEMBL31267447 | 0.76 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9229366 | 0.76 | NAMPT (0.55) | KDM4ELMNANAMPTNPC1RAB9A | |
| SCHEMBL9227977 | 0.76 | TERT (0.44) | NAMPTTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |