Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14576206 | 0.82 | KMT2A (0.62) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL3622325 | 0.81 | VCAM1 (0.76) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL9225412 | 0.80 | KDM4E (0.55) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL8854767 | 0.80 | ALDH1A1 (0.67) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL15646636 | 0.80 | ALDH1A1 (0.67) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL17841231 | 0.80 | LMNA (0.76) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL29483590 | 0.80 | LMNA (0.76) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL29483577 | 0.80 | LMNA (0.76) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL20380049 | 0.77 | ALDH1A1 (0.63) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL20379393 | 0.77 | ALDH1A1 (0.63) | KMT2AALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |