Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220176 | 0.98 | TSHR (0.35) | TSHR | |
| SCHEMBL9224823 | 0.84 | TSHR (0.36) | TSHR | |
| SCHEMBL9219987 | 0.82 | CHRNA7 (0.31) | — | |
| SCHEMBL9220570 | 0.82 | TSHR (0.35) | TSHR | |
| SCHEMBL18918251 | 0.81 | HTR2A (0.37) | TSHRMEN1KMT2AHTR2ATAAR1 | |
| SCHEMBL9218213 | 0.81 | GAA (0.32) | — | |
| SCHEMBL28263737 | 0.79 | TSHR (0.41) | TSHRMEN1KMT2AHTR2ATAAR1 | |
| SCHEMBL9220265 | 0.78 | TSHR (0.44) | TSHRHTR2ATAAR1 | |
| SCHEMBL9226120 | 0.75 | TSHR (0.41) | TSHRMEN1KMT2A | |
| SCHEMBL9226300 | 0.74 | TSHR (0.40) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118879-A | Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0420987-A1 | Process for preparing fluoroalkyl derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | claimed |
| EP-0420987-B1 | Process for preparing fluoroalkyl derivatives | NIPPON OILS & FATS CO LTD (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5118879-A | Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0420987-A1 | Process for preparing fluoroalkyl derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | disclosed |