SCHEMBL9219987

SCHEMBL9219987

Cc1ccc(C(Cl)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218213 0.98 GAA (0.32) GAA
SCHEMBL9224823 0.84 TSHR (0.36)
SCHEMBL9220570 0.83 TSHR (0.35)
SCHEMBL9225482 0.82 TSHR (0.37)
SCHEMBL9220176 0.81 TSHR (0.35)
SCHEMBL9227730 0.80 CHRNA7 (0.35) CHRNA7
SCHEMBL29832138 0.72 CA2 (0.41) GAA
SCHEMBL28320895 0.72
SCHEMBL29831769 0.69 ALDH1A1 (0.42) GAA
SCHEMBL25693125 0.67 IDO1 (0.37) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118879-A Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents NIPPON OIL AND FATS CO., LTD. (JP) 1992-06-02 US claimed
EP-0420987-A1 Process for preparing fluoroalkyl derivatives NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-04-10 EP claimed
EP-0420987-B1 Process for preparing fluoroalkyl derivatives NIPPON OILS & FATS CO LTD (JP) 1995-05-03 EP disclosed
US-5118879-A Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents NIPPON OIL AND FATS CO., LTD. (JP) 1992-06-02 US disclosed
EP-0420987-A1 Process for preparing fluoroalkyl derivatives NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-04-10 EP disclosed