1,2-Naphthoquinone

1,2-Naphthoquinone

SCHEMBL9225610

O=C1C=Cc2ccccc2C1=O.[N-]=[N+]=N

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 8/20 0.77
PTPN1 P18031 5/20 0.77
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
KDM4E B2RXH2 4/20 0.77
CES1 P23141 3/20 0.77
MAPT P10636 3/20 0.77
IDO1 P14902 2/20 0.77
LMNA P02545 2/20 0.77
BCHE P06276 2/20 0.77
POLB P06746 2/20 0.77
THRB P10828 2/20 0.77
RECQL P46063 2/20 0.77
ALDH1A1 P00352 2/20 0.77
HPGD P15428 2/20 0.77
PTPN22 Q9Y2R2 2/20 0.77
PKM P14618 1/20 0.77
ALOX15 P16050 1/20 0.77
ACHE P22303 1/20 0.77
HSD17B10 Q99714 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Naphthoquinone SCHEMBL203171 0.98 PTPRC (0.74) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL9225602 0.92 PTPRC (0.83) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL29368763 0.92 PTPRC (0.83) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL20212026 0.92 PTPRC (0.83) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL5147399 0.92 PTPRC (0.65) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL10930514 0.89 PTPRC (0.61) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL173316 0.88 PTPRC (1.00) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL15167712 0.88 PTPRC (1.00) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL29363665 0.88 PTPRC (1.00) PTPRCPTPN1MEN1KMT2AKDM4E
1,2-Naphthoquinone SCHEMBL30697786 0.86 PTPRC (0.95) PTPRCPTPN1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7248619-A None JP disclosed
EP-2505576-B1 CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL CO (JP) 2019-04-24 EP disclosed
EP-2599814-B1 COMPOUND, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN MITSUBISHI GAS CHEMICAL CO (JP) 2018-02-14 EP disclosed
US-9239517-B2 Compound, radiation-sensitive composition and resist pattern formation method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-01-19 US disclosed
US-8969629-B2 Cyclic compound, production process thereof, radiation-sensitive composition and resist pattern formation method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-03-03 US disclosed
EP-2599814-A1 COMPOUND, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN Mitsubishi Gas Chemical Company, Inc. (JP) 2013-06-05 EP disclosed
US-20130122423-A1 COMPOUND, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-05-16 US disclosed
US-20120282546-A1 CYCLIC COMPOUND, PRODUCTION PROCESS THEREOF, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-11-08 US disclosed
EP-2505576-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD Mitsubishi Gas Chemical Company, Inc. (JP) 2012-10-03 EP disclosed
JP-H07248619-A POSITIVE TYPE PHOTO-RESIST COMPOSITION TOPPAN PRINTING CO LTD 1995-09-26 JP disclosed
US-4740450-A COATING WITH PHOTOSENSITIVE LAYER CONTAINING SCRATCH IMPROVER; DRYING, MIGRATION TOYO BOSEKI KABUSHIKI KAISHA (JP) 1988-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130122423-A1 COMPOUND, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD DDB1, DNAJB11, RAD51 PTPRC 3834/4885PTPN1 3325/4885MEN1 1983/4885
US-20120282546-A1 CYCLIC COMPOUND, PRODUCTION PROCESS THEREOF, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD CROCC, XRCC6, CHEK1 PTPRC 3273/4885PTPN1 2963/4885MEN1 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.