SCHEMBL9225813

SCHEMBL9225813

CCOc1ccc(-c2ccc(-c3ccc(OC(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.46
PPARD Q03181 3/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 2/20 0.43
NQO1 P15559 1/20 0.42
GRIN2B Q13224 1/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
RARA P10276 1/20 0.39
RARB P10826 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CYP17A1 P05093 1/20 0.38
ERN1 O75460 1/20 0.37
CACNA1C Q13936 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9228824 0.93 FFAR1 (0.42) FFAR1PPARDMEN1KMT2ARAB9A
SCHEMBL9224650 0.92 FFAR1 (0.41) FFAR1PPARDMEN1KMT2ARAB9A
SCHEMBL9220464 0.88 RARA (0.45) RAB9AGRIN2BRARARARBKDM4E
SCHEMBL9228392 0.88 RARB (0.51) RAB9ARARARARBKDM4ENPC1
SCHEMBL9223515 0.86 RARB (0.49) RARARARB
SCHEMBL9219171 0.85 RARB (0.48) RARARARBTSHR
SCHEMBL9228557 0.83 RARB (0.46) PPARDRARARARB
SCHEMBL9226641 0.83 RARA (0.41) FFAR1PPARDRAB9ARARARARB
SCHEMBL9228953 0.82 PTGS2 (0.42) FFAR1PPARDMEN1KMT2ARAB9A
SCHEMBL9225258 0.82 PTGS2 (0.42) FFAR1PPARDMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-B1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK PATENT GMBH (DE) 1995-12-20 EP disclosed
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed