Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.67 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20961846 | 0.93 | LOXL2 (0.60) | LOXL2CALM1PNMTENPP2TAAR1 | |
| SCHEMBL13003829 | 0.88 | LOXL2 (0.62) | LOXL2CALM1PNMTENPP2PRSS1 | |
| SCHEMBL2570218 | 0.87 | LOXL2 (0.78) | LOXL2CALM1PRSS1PRSS2PRSS3 | |
| SCHEMBL13971231 | 0.87 | CALM1 (0.75) | LOXL2CALM1PRSS1PRSS2PRSS3 | |
| SCHEMBL7613502 | 0.87 | CALM1 (0.75) | LOXL2CALM1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL921946 | 0.85 | LOXL2 (0.74) | LOXL2CALM1PRSS1PRSS2PRSS3 | |
| SCHEMBL30350846 | 0.85 | LOXL2 (0.63) | LOXL2PNMTENPP2TAAR1PRMT6 | |
| SCHEMBL15345357 | 0.85 | ASIC3 (0.58) | LOXL2CALM1PNMTENPP2PRSS1 | |
| SCHEMBL36008 | 0.84 | LOXL2 (0.71) | LOXL2PNMTENPP2TAAR1PRMT6 | |
| SCHEMBL10422276 | 0.84 | LOXL2 (0.71) | LOXL2PNMTENPP2TAAR1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884687-B | A kind of preparation method of 5- benzyls benzydamine | 梯尔希（南京）药物研发有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-105884687-A | Preparation method of 5-benzyl benzydamine | 梯尔希（南京）药物研发有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-105884687-B | A kind of preparation method of 5- benzyls benzydamine | 梯尔希（南京）药物研发有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-105884687-B | A kind of preparation method of 5- benzyls benzydamine | 梯尔希（南京）药物研发有限公司 | 2018-06-22 | — | — | CN | disclosed |
| EP-1773786-B1 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2657214-B1 | PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL | MITSUBISHI GAS CHEMICAL CO (JP) | 2017-02-15 | — | — | EP | disclosed |
| CN-105884687-A | Preparation method of 5-benzyl benzydamine | 梯尔希（南京）药物研发有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105884687-A | Preparation method of 5-benzyl benzydamine | 梯尔希（南京）药物研发有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-105884687-A | Preparation method of 5-benzyl benzydamine | 梯尔希（南京）药物研发有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-103298772-B | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2015-06-24 | — | — | CN | disclosed |
| US-8993774-B2 | Process for production of aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-03-31 | — | — | US | disclosed |
| WO-1998038177-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR INHIBITING β-AMYLOID PEPTIDE | ELAN PHARMACEUTICALS, INC. (US) | 1998-09-03 | — | — | WO | disclosed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| CN-1050376-A | Acyl-CoA: cholesterol acyltransferase inhibitor | WARBER LAMBERT CO (US) | 1991-04-03 | — | — | CN | disclosed |
| EP-0006180-B1 | 3-PHENOXYBENZYLIDENE AMINES AND 3-BENZYLBENZYLIDENE AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE THE CORRESPONDING ALDEHYDES | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |
| US-4231962-A | 3-Phenoxybenzylideneamines and 3-benzylbenzylideneamines | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0006180-A1 | 3-Phenoxybenzylidene amines and 3-benzylbenzylidene amines, process for their preparation and their use to prepare the corresponding aldehydes | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006155-A1 | 3-Phenoxybenzyl amines and 3-benzylbenzyl amines and process for their production | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006155-A1 | 3-Phenoxybenzyl amines and 3-benzylbenzyl amines and process for their production | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006155-A1 | 3-Phenoxybenzyl amines and 3-benzylbenzyl amines and process for their production | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |