Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263434 | 0.79 | CYP2C19 (0.49) | ALDH1A1CYP2C19VCPTSHRCYP3A4 | |
| SCHEMBL25771 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| SCHEMBL1734014 | 0.78 | CYP2C19 (0.47) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| SCHEMBL8505313 | 0.78 | CYP2C19 (0.50) | ALDH1A1CYP2C19VCPTSHRMAPT | |
| SCHEMBL10759367 | 0.76 | CYP2C19 (0.50) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| Water SCHEMBL7268737 | 0.74 | ALDH1A1 (0.49) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| SCHEMBL3042994 | 0.74 | CYP2C19 (0.52) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| Bromide SCHEMBL7268772 | 0.74 | CYP2C19 (0.49) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| SCHEMBL5373513 | 0.72 | ALDH1A1 (0.47) | ALDH1A1CYP2C19VCPCYP19A1PTGS2 | |
| SCHEMBL11304731 | 0.72 | ACHE (0.44) | ALDH1A1CYP2C19TSHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451683-A | Spatially-addressable immobilization of anti-ligands on surfaces | AFFYMAX TECHNOLOGIES N.V. | 1995-09-19 | — | — | US | claimed |
| EP-0502060-A4 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | — | 1993-05-05 | — | — | EP | claimed |
| EP-0502060-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007087-A1 | SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1991-05-30 | — | — | WO | claimed |