Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227461 | 0.78 | ALDH1A1 (0.45) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL25771 | 0.78 | ALDH1A1 (0.45) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8505313 | 0.77 | CYP2C19 (0.50) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL7263434 | 0.75 | CYP2C19 (0.49) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL10759367 | 0.74 | CYP2C19 (0.50) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8167083 | 0.74 | ALDH1A1 (0.38) | CYP2C19ALDH1A1MAPTHTTTNF | |
| Bromide SCHEMBL7268772 | 0.73 | CYP2C19 (0.49) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| Water SCHEMBL7268737 | 0.73 | ALDH1A1 (0.49) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL3042994 | 0.73 | CYP2C19 (0.52) | CYP2C19ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL20592075 | 0.73 | ALDH1A1 (0.49) | CYP2C19ALDH1A1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816962-A | Synthesis of Bruton's tyrosine kinase inhibitors | 药品循环有限责任公司 | 2021-12-21 | — | — | CN | disclosed |
| EP-1896452-B1 | N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2011-11-16 | — | — | EP | disclosed |
| US-8044199-B2 | N-formyl hydroxylamines compounds | VICURON HOLDINGS LLC (US) | 2011-10-25 | — | — | US | disclosed |
| US-20100063278-A1 | N-Formyl Hydroxylamines compounds | NOVARTIS AG (CH) | 2010-03-11 | — | — | US | disclosed |
| US-20090318445-A1 | PDF INHIBITORS | NORVARTIS AG (CH) | 2009-12-24 | — | — | US | disclosed |
| US-7615635-B2 | N-formyl hydroxylamines | NOVARTIS AG (CH) | 2009-11-10 | — | — | US | disclosed |
| US-20090062537-A1 | N-Formyl Hydrozyamine Compounds | LEE KWANGHO | 2009-03-05 | — | — | US | disclosed |
| EP-1973898-A1 | PDF INHIBITORS | Novartis AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| US-20080161558-A1 | 1-[2-Cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionyl]-pyrrolidine-2-carboxylic acid (5-fluoro-1-oxy-pyridin-2-yl)-amide; inhibitors of peptidyl deformylase (PDF), antimicrobials and antibiotics | VICURON HOLDINGS LLC | 2008-07-03 | — | — | US | disclosed |
| EP-1896452-A2 | N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis Pharma AG. (CH) | 2008-03-12 | — | — | EP | disclosed |
| US-5917016-A | USEFUL AS PHOTOCLEAVABLE LINKING GROUPS IN SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5874589-A | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof | GLAXO WELLCOME, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-5846839-A | Methods for hard-tagging an encoded synthetic library | GLAXO GROUP LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| WO-1998018754-A1 | METHODS FOR SOLID-PHASE SYNTHESIS OF HYDROXYLAMINE COMPOUNDS AND DERIVATIVES, AND COMBINATORIAL LIBRARIES THEREOF | VERSICOR, INC. (US) | 1998-05-07 | — | — | WO | disclosed |
| US-5739386-A | PHOTOCLEAVABLE LINKING GROUPS IN SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-14 | — | — | US | disclosed |
| WO-1997041093-A1 | METHODS FOR THE SYNTHESIS OF FMOC PROTECTED AMINES | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-11-06 | — | — | WO | disclosed |
| EP-0776330-A2 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1997-06-04 | — | — | EP | disclosed |
| US-5549974-A | IMMOBILIZATION | AFFYMAX TECHNOLOGIES NV (AN) | 1996-08-27 | — | — | US | disclosed |
| WO-1996000378-A1 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995018971-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF GLYCOCONJUGATES | AFFYMAX TECHNOLOGIES N.V. (NL) | 1995-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063278-A1 | N-Formyl Hydroxylamines compounds | PDF, MMP2, HNMT | CYP2C19 1053/4885ALDH1A1 1461/4885PPARG 4095/4885 |
| US-20090062537-A1 | N-Formyl Hydrozyamine Compounds | PDF, HNMT, MMP2 | CYP2C19 936/4885ALDH1A1 1755/4885PPARG 4352/4885 |
| US-20090318445-A1 | PDF INHIBITORS | PDF, TIMP3, MMP2 | CYP2C19 1977/4885ALDH1A1 2901/4885PPARG 4478/4885 |
| US-20080161558-A1 | 1-[2-Cyclopentylmethyl-3-(formyl-hydroxy-amino)-propionyl]-pyrrolidine-2-carboxylic acid (5-fluoro-1-oxy-pyridin-2-yl)-amide; inhibitors of peptidyl deformylase (PDF), antimicrobials and antibiotics | PDF, MMP2, PEPD | CYP2C19 1509/4885ALDH1A1 1080/4885PPARG 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.