Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884294 | 0.90 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL12233464 | 0.84 | POLB (0.53) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9228703 | 0.83 | HTR6 (0.54) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL9230987 | 0.83 | GAA (0.61) | MAPTALDH1A1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL9231987 | 0.81 | HTR6 (0.52) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL9230339 | 0.81 | HTR6 (0.59) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL9228688 | 0.79 | ALDH1A1 (0.65) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL9232433 | 0.79 | PKM (0.66) | MAPTALDH1A1IDO1CA2CA1 | |
| SCHEMBL9234891 | 0.77 | PKM (0.68) | MAPTALDH1A1MEN1KMT2AATM | |
| SCHEMBL9233195 | 0.77 | KMT2A (0.60) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |