Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883549 | 0.88 | MAPT (0.50) | MAPTKMT2ALMNAMAPK1ALDH1A1 | |
| SCHEMBL13884294 | 0.86 | ALDH1A1 (0.55) | MAPTKMT2ALMNAKDM4EMAPK1 | |
| SCHEMBL9234891 | 0.83 | PKM (0.68) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL4027167 | 0.82 | MAPT (0.61) | MAPTKMT2ALMNAKDM4EMAPK1 | |
| SCHEMBL9230987 | 0.79 | GAA (0.61) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9228703 | 0.79 | HTR6 (0.54) | MAPTKMT2ALMNAKDM4EMAPK1 | |
| SCHEMBL9228034 | 0.79 | MAPT (0.42) | MAPTKMT2ALMNAKDM4EMAPK1 | |
| SCHEMBL23239821 | 0.78 | KMT2A (0.57) | MAPTKMT2ALMNAKDM4EMAPK1 | |
| SCHEMBL9231499 | 0.78 | HPGD (0.66) | MAPTKMT2ALMNAMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9231987 | 0.77 | HTR6 (0.52) | MAPTKMT2ALMNAKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666253-A1 | N-t-BUTYLANILINE ANALOG AND LIPID LEVEL DEPRESSANT CONTAINING THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-08-09 | — | — | EP | disclosed |