Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.60 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 3/20 | 0.60 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808189 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9223153 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9221587 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL591362 | 0.83 | KDM4E (0.78) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Oxamarin SCHEMBL628427 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9367076 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL12475243 | 0.79 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6589340 | 0.79 | MAOB (0.68) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Oxamarin SCHEMBL30398534 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| Oxamarin SCHEMBL635068 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439828-A | Fluorgenic and chomogenic three-dimensional ionophores as selective reagents for detecting ions in biological fluids | ALLIEDSIGNAL INC. (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0371992-B1 | IONOPHORES AS REAGENTS FOR DETECTING IONS | ALLIED SIGNAL INC (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5162525-A | FLUOROGENIC AND CHROMOGENIC THREE-DIMENSIONAL IONOPHORES AS SELECTIVE REAGENTS FOR DETECTING IONS IN BIOLOGICAL FLUIDS | ALLIED-SIGNAL INC. (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0371992-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS. | ALLIED SIGNAL INC (US) | 1990-06-13 | — | — | EP | disclosed |
| WO-1989000997-A1 | IONOPHORES AS REAGENTS FOR DETECTING IONS | ALLIED-SIGNAL INC. (US) | 1989-02-09 | — | — | WO | disclosed |
| EP-0031202-B1 | NEW POLYESTER COMPOSITIONS; SHAPED ARTICLES OBTAINED FROM THEM AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-03 | — | — | EP | disclosed |
| US-4347350-A | Polyester compositions containing residues of dihydroxyalkoxy coumarins | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-08-31 | — | — | US | disclosed |
| EP-0031202-A2 | New polyester compositions; shaped articles obtained from them and processes for preparing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-01 | — | — | EP | disclosed |