Oxamarin

Oxamarin

SCHEMBL628427

CCN(CC)CCOc1cc2oc(=O)cc(C)c2cc1OCCN(CC)CC

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 7/20 0.51
HPGD P15428 5/20 0.51
HSD17B10 Q99714 4/20 0.51
GLA P06280 3/20 0.51
CASP1 P29466 2/20 0.51
CASP7 P55210 2/20 0.51
GAA P10253 2/20 0.51
MAPT P10636 2/20 0.51
HSP90AA1 P07900 1/20 0.51
HSP90AB1 P08238 1/20 0.51
ALPG P10696 1/20 0.51
ALOX15 P16050 1/20 0.51
ALOX12 P18054 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
IGLV6-57 P01721 4/20 0.47
CYP3A4 P08684 2/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxamarin SCHEMBL30398534 0.99 KDM4E (0.53) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
Oxamarin SCHEMBL635068 0.99 KDM4E (0.53) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL591362 0.81 KDM4E (0.78) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL9229347 0.80 KDM4E (0.60) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL9223153 0.80 KDM4E (0.59) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL9221587 0.80 KDM4E (0.56) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL9367076 0.76 KDM4E (0.54) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL8808189 0.75 KDM4E (0.53) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL4611432 0.73 KDM4E (0.58) KDM4ECYP1A2CYP2C19ALDH1A1HPGD
SCHEMBL30819091 0.73 KDM4E (0.66) KDM4ECYP1A2CYP2C19ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9649093-B2 Cavity-filling biopsy site markers SENORX, INC. (US) 2017-05-16 US claimed
US-20160120510-A1 CAVITY-FILLING BIOPSY SITE MARKERS SENORX, INC. 2016-05-05 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20120121724-A1 FILM COMPRISING THERAPEUTIC AGENTS MAIBACH TODD (US) 2012-05-17 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20070059346-A1 Film comprising therapeutic agents ACADERM, INC. 2007-03-15 US claimed
CN-1829490-A Films comprising therapeutic agents TODD MAIBACH (US) 2006-09-06 CN claimed
EP-1648362-A2 FILM COMPRISING THERAPEUTIC AGENTS Maibach, Todd (US) 2006-04-26 EP claimed
US-20050234336-A1 Apparatus and method for marking tissue GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2005-10-20 US claimed
US-6862470-B2 Cavity-filling biopsy site markers SENORX, INC. (US) 2005-03-01 US claimed
WO-2005004989-A2 FILM COMPRISING THERAPEUTIC AGENTS MAIBACH TODD (US) 2005-01-20 WO claimed
EP-1494721-A2 CAVITY FILLING BIOPSY SITE MARKER Senorx, Inc. (US) 2005-01-12 EP claimed
WO-2003089012-A2 CAVITY FILLING BIOPSY SITE MARKER SENORX, INC. (US) 2003-10-30 WO claimed
US-20020188196-A1 Cavity-filling biopsy site markers SENORX, INC. 2002-12-12 US claimed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
WO-1999004828-A2 USE OF HYALURONIC ACID DERIVATIVES IN THE PREPARATION OF BIOMATERIALS FIDIA ADVANCED BIOPOLYMERS, S.R.L. (IT) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 KDM4E 2452/4885CYP1A2 1810/4885CYP2C19 1403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.