Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9234867 | 0.82 | MEN1 (0.55) | LMNAALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9058562 | 0.76 | ALDH1A1 (0.46) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL9053926 | 0.71 | CYP1A2 (0.36) | KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL9058881 | 0.70 | KDM4E (0.46) | ALDH1A1CYP2C19HTTCYP1A2CYP2C9 | |
| SCHEMBL9058693 | 0.68 | MAPK1 (0.43) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL9058728 | 0.66 | GSTP1 (0.42) | ALDH1A1KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL8089226 | 0.66 | — | — | |
| SCHEMBL9058875 | 0.65 | KDM4E (0.54) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9059134 | 0.65 | GLA (0.37) | LMNAALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL9061671 | 0.65 | RXFP1 (0.43) | LMNAALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632040-A1 | Antibacterial imidazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-01-04 | — | — | EP | claimed |
| EP-0632040-A1 | Antibacterial imidazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |