SCHEMBL9058693

SCHEMBL9058693

CC(O)CSc1ccc2ncc([N+](=O)[O-])n2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.43
ATM Q13315 1/20 0.43
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CHRM1 P11229 1/20 0.36
LMNA P02545 3/20 0.34
ALDH1A1 P00352 2/20 0.34
THRB P10828 1/20 0.34
TSHR P16473 1/20 0.34
LRRK2 Q5S007 1/20 0.33
GAA P10253 1/20 0.32
TYMS P04818 1/20 0.31
KDM4E B2RXH2 2/20 0.31
DYRK3 O43781 1/20 0.30
CCNT1 O60563 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CDK9 P50750 1/20 0.30
CDK5 Q00535 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058562 0.81 ALDH1A1 (0.46) MAPK1ATMCYP1A2CYP2C9CHRM1
SCHEMBL9058881 0.80 KDM4E (0.46) CYP1A2CYP2C9ALDH1A1GAAKDM4E
SCHEMBL9059354 0.80 LMNA (0.34) MAPK1ATMCYP1A2CYP2C9LMNA
SCHEMBL9058728 0.78 GSTP1 (0.42) CYP1A2CYP2C9ALDH1A1GAAKDM4E
SCHEMBL9058875 0.77 KDM4E (0.54) CYP1A2CYP2C9LMNAALDH1A1TSHR
SCHEMBL9059134 0.77 GLA (0.37) CYP1A2CYP2C9LMNAALDH1A1LRRK2
SCHEMBL9058574 0.75 MAPK1 (0.42) MAPK1ATMCYP1A2CYP2C9CHRM1
SCHEMBL9058576 0.74 CA1 (0.37) MAPK1CYP1A2CYP2C9LMNAKDM4E
Hydrochloric Acid SCHEMBL9061671 0.74 RXFP1 (0.43) LMNAALDH1A1TSHRGAAKDM4E
SCHEMBL9058568 0.73 ALDH1A1 (0.39) CYP1A2CYP2C9ALDH1A1KDM4EDYRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996016656-A1 CONDENSED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-06-06 WO disclosed