SCHEMBL9229365

SCHEMBL9229365

COCCNC(=O)c1ccc(CCl)cc1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.67
HPGD P15428 4/20 0.62
KMT2A Q03164 3/20 0.60
NPC1 O15118 4/20 0.53
RAB9A P51151 2/20 0.53
NAMPT P43490 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
MEN1 O00255 1/20 0.50
TP53 P04637 1/20 0.50
POLB P06746 1/20 0.50
LMNA P02545 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21674211 0.87 SMN1; SMN2 (0.65) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL21674205 0.86 CA1 (0.55) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL2056358 0.85 HPGD (0.64) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL13009924 0.85 ALDH1A1 (0.54) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL7445362 0.85 HPGD (0.64) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL19465880 0.83 HPGD (0.62) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL19634404 0.83 LOXL2 (0.64) ALDH1A1HPGDKMT2ANPC1NAMPT
SCHEMBL28511410 0.83 SMN1; SMN2 (0.59) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL12964846 0.83 ALDH1A1 (0.57) ALDH1A1NPC1RAB9ASMN1; SMN2POLB
SCHEMBL21674210 0.82 MAPK1 (0.62) ALDH1A1NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790245-B2 Water soluble catalysts for NMR/MRI enhancement VANDERBILT UNIVERSITY (US) 2017-10-17 US disclosed
EP-0661266-A1 Substituted cyclic amine compounds as 5HT2 antagonists TOA EIYO LTD. (JP) 1995-07-05 EP disclosed