Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9331456 | 0.87 | HCAR2 (0.39) | ALDH1A1HCAR2LMNAESR1CHRM1 | |
| SCHEMBL722005 | 0.75 | — | — | |
| SCHEMBL1363002 | 0.75 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL6179801 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HCAR2LMNAESR1CHRM1 | |
| SCHEMBL439275 | 0.73 | — | — | |
| SCHEMBL3782478 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HCAR2LMNATSHRHSD17B10 | |
| SCHEMBL27519089 | 0.71 | — | — | |
| SCHEMBL2370219 | 0.71 | — | — | |
| SCHEMBL11521868 | 0.71 | ALDH1A1 (0.57) | ALDH1A1HCAR2LMNAESR1TSHR | |
| SCHEMBL6786247 | 0.71 | HCAR2 (0.43) | ALDH1A1HCAR2LMNAESR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648769-A1 | 12-Hetero-substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizium salts and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5380729-A | Treatment or prevention of neurodegenerative disorders or neurotoxic injuries | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |