Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 13/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.73 |
| ▸ | DRD2 | P14416 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844907 | 0.93 | HTR1A (0.88) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL6751064 | 0.85 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL14416822 | 0.82 | HTR1A (0.78) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| Bmy-7378 SCHEMBL6017145 | 0.80 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| Bmy-7378 SCHEMBL32690868 | 0.80 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL6580134 | 0.79 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| Bmy-7378 SCHEMBL987183 | 0.79 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL9844858 | 0.78 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL6752779 | 0.76 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL6752752 | 0.76 | HTR1A (0.76) | HTR1AADRA1BADRA1AADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8092221-A | — | — | None | — | — | JP | disclosed |
| JP-H0892221-A | NEW AZASPIRO(4,5)DECANE-7,9-DIONE DERIVATIVE | FAB ESPANOLA DE PROD QUIMICOS I FARMACEUT SA | 1996-04-09 | — | — | JP | disclosed |