Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.69 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844900 | 0.94 | HTR1A (0.88) | HTR1AADRA1BADRA1AHTR7DRD2 | |
| SCHEMBL10521533 | 0.84 | HTR1A (0.72) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10566798 | 0.83 | HTR1A (0.71) | HTR1AHTR7 | |
| SCHEMBL6580134 | 0.82 | HTR1A (1.00) | HTR1AADRA1BADRA1ADRD2ADRA1D | |
| SCHEMBL6754644 | 0.80 | HTR1A (1.00) | HTR1AADRA1BADRA1ADRD2ADRA1D | |
| SCHEMBL7668123 | 0.79 | HTR7 (0.95) | HTR1AHTR7DRD2 | |
| SCHEMBL6865196 | 0.78 | HTR7 (0.87) | HTR1AHTR7DRD2 | |
| SCHEMBL9229653 | 0.78 | HTR1A (1.00) | HTR1AADRA1BADRA1ADRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL6866824 | 0.78 | HTR7 (0.93) | HTR1AHTR7DRD2 | |
| Hydrochloric Acid SCHEMBL7663753 | 0.77 | HTR7 (0.85) | HTR1AHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447345-A2 | New Azaspyro [4.5] decane-7,9-dione derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1991-09-18 | — | — | EP | claimed |