Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.88 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229653 | 0.93 | HTR1A (1.00) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL16406365 | 0.79 | HTR1A (0.74) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL9844900 | 0.79 | HTR1A (0.88) | HTR1AADRA1BDRD2ADRA1AHTR7 | |
| Hydrochloric Acid SCHEMBL9545425 | 0.79 | HTR1A (0.64) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL6751064 | 0.78 | HTR1A (1.00) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL16406392 | 0.77 | HTR1A (0.71) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL14416822 | 0.76 | HTR1A (0.78) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL10441355 | 0.76 | HTR1A (0.75) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL2091264 | 0.75 | DRD2 (0.57) | HTR1AADRA1BDRD2ADRA1AADRA1D | |
| SCHEMBL3209314 | 0.75 | DRD2 (0.57) | HTR1AADRA1BDRD2ADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447345-A2 | New Azaspyro [4.5] decane-7,9-dione derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1991-09-18 | — | — | EP | disclosed |