SCHEMBL922968

SCHEMBL922968

O=S(=O)(O)CCCCO.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
LMNA P02545 5/20 0.41
BLM P54132 2/20 0.41
PTGS1 P23219 1/20 0.41
PDE4A P27815 1/20 0.41
SLC6A6 P31641 1/20 0.41
CYP2C19 P33261 1/20 0.41
CA2 P00918 5/20 0.39
EPHX2 P34913 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 3/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30
POLB P06746 2/20 0.30
RAB9A P51151 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4105848 0.97 APP (0.48) APPLMNABLMPTGS1PDE4A
SCHEMBL10885090 0.97 APP (0.48) APPLMNABLMPTGS1PDE4A
SCHEMBL3001162 0.97 APP (0.48) APPLMNABLMPTGS1PDE4A
SCHEMBL51852 0.97
SCHEMBL11596772 0.94 APP (0.50) APPLMNABLMPTGS1PDE4A
SCHEMBL11039416 0.94 APP (0.50) APPLMNABLMPTGS1PDE4A
SCHEMBL9822644 0.94 APP (0.50) APPLMNABLMPTGS1PDE4A
SCHEMBL10591208 0.94 APP (0.50) APPLMNABLMPTGS1PDE4A
SCHEMBL841751 0.94 APP (0.50) APPLMNABLMPTGS1PDE4A
SCHEMBL5888595 0.94 APP (0.50) APPLMNABLMPTGS1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146124-A Sulfonate containing ester group, preparation process and application thereof 苏州祺添新材料股份有限公司 2024-06-07 CN claimed
CN-116396461-A Isocyanate-terminated prepolymer, application thereof and polyurethane adhesive prepared from prepolymer 北京大清生物技术股份有限公司 2023-07-07 CN claimed
CN-112912108-A Cyclodextrin-based formulations of BCL-2 inhibitors 法国施维雅药厂 2021-06-04 CN claimed
CN-111499547-A Preparation method and application of alkyl ether sulfonyl fluoride compound 江汉大学 2020-08-07 CN claimed
EP-1054664-A1 METHOD FOR MODULATING MACROPHAGE ACTIVATION Neurochem, Inc. (CA) 2000-11-29 EP claimed
WO-1999040909-A1 METHOD FOR MODULATING MACROPHAGE ACTIVATION NEUROCHEM, INC. (CA) 1999-08-19 WO claimed
CN-118146124-A Sulfonate containing ester group, preparation process and application thereof 苏州祺添新材料股份有限公司 2024-06-07 CN disclosed
CN-115160191-B Method for preparing alkylphenol polyoxyethylene ether sulfonate 中国石油大学(华东) 2024-04-26 CN disclosed
EP-3831388-B1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FOR USE IN SUPPRESSING ADENOVIRUS FUJIFILM CORP (JP) 2024-02-28 EP disclosed
US-20230382892-A1 Chemical Compounds PFIZER INC. (US) 2023-11-30 US disclosed
US-20230295202-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM CORPORATION (JP) 2023-09-21 US disclosed
EP-3831836-B1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM CORP (JP) 2023-09-06 EP disclosed
US-11702405-B2 Chemical compounds PFIZER INC. (US) 2023-07-18 US disclosed
US-5858326-A CONTACTING AMYLOIDOGENIC PEPTIDE WITH AMYLOID-ENHANCING COMPOUND COMPRISING AROMATIC MOIETY AND AT LEAST TWO ANIONIC MOIETIES IN VITRO TO FORM AMYLOID FIBRILS NEUROCHEM, INC. (CA) 1999-01-12 US disclosed
US-5728375-A ADMINISTERING A COMPOUND COMPRISING AN ANIONIC GROUP AND A CARRIER MOLECULE; INHIBITS DEPOSITION BY PREVENTING INTERACTION BETWEEN AN AMYLOIDOGENIC PROTEIN AND A BASEMENT MEMBRANE CONSTITUENT QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-03-17 US disclosed
US-5643562-A ANTIDEPOSIT AGENTS FOR PROTEINS FOR MEDICAL DIAGNOSIS OF DISEASES QUEEN'S UNIVERSITY OF KINGSTON (CA) 1997-07-01 US disclosed
EP-0062430-B1 PROCESS FOR THE PREPARATION OF (OMEGA-FLUOROSULFONYL) HALOALIPHATIC CARBOXYLIC ACID FLUORIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-11-12 EP disclosed
US-4466881-A ELECROLYTIC FLUORINATION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-08-21 US disclosed
US-4425199-A FLUORINATION, ELECTROLYSIS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-01-10 US disclosed
EP-0062430-A1 Process for the preparation of (omega-fluorosulfonyl) haloaliphatic carboxylic acid fluorides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295202-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF SLC28A1, SLC20A1, SLC29A1 APP 2279/4885LMNA 2968/4885BLM 532/4885
US-11702405-B2 Chemical compounds HBZ, HBB, HBS1L APP 1293/4885LMNA 748/4885BLM 1630/4885
US-20230382892-A1 Chemical Compounds HBZ, HBB, HBS1L APP 1293/4885LMNA 748/4885BLM 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.