Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924114 | 0.97 | HTR1A (0.34) | HTR1AFFAR1HDAC6NPC1NFKB1 | |
| SCHEMBL9283372 | 0.89 | FFAR1 (0.33) | HTR1AFFAR1MAOAMAOBCYP2C8 | |
| SCHEMBL8553780 | 0.80 | NPC1 (0.36) | HTR1AFFAR1HDAC6NPC1NFKB1 | |
| SCHEMBL8603712 | 0.77 | NR1I2 (0.37) | HTR1ANPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL8604570 | 0.76 | HDAC6 (0.38) | FFAR1HDAC6NPC1NFKB1RAB9A | |
| SCHEMBL8551826 | 0.76 | FFAR4 (0.44) | FFAR1HDAC6MEN1KMT2AUSP2 | |
| SCHEMBL8553057 | 0.76 | KMT2A (0.34) | FFAR1HDAC6NPC1NFKB1RAB9A | |
| SCHEMBL8553882 | 0.75 | HDAC6 (0.37) | FFAR1HDAC6NPC1NFKB1RAB9A | |
| SCHEMBL8553434 | 0.75 | MEN1 (0.36) | FFAR1HDAC6NPC1NFKB1RAB9A | |
| SCHEMBL8555548 | 0.75 | LMNA (0.40) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |
| WO-1995031452-A1 | THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |