Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234662 | 0.92 | AR (0.50) | ARMAPTTHRBL3MBTL1POLB | |
| SCHEMBL9237047 | 0.87 | DHFR (0.53) | ARMAPTL3MBTL1LMNARNASEH1 | |
| SCHEMBL9231896 | 0.87 | DHODH (0.46) | MAPTTHRBL3MBTL1POLBLMNA | |
| SCHEMBL9235475 | 0.84 | AR (0.59) | ARMAPTTHRBLMNAALDH1A1 | |
| SCHEMBL9233264 | 0.81 | DHODH (0.47) | MAPTTHRBL3MBTL1POLBLMNA | |
| SCHEMBL9238060 | 0.80 | DHODH (0.48) | MAPTL3MBTL1POLBLMNAALDH1A1 | |
| SCHEMBL9235625 | 0.79 | DHFR (0.56) | ARMAPTTHRBLMNAALDH1A1 | |
| SCHEMBL9233991 | 0.77 | DHFR (0.48) | MAPTTHRBL3MBTL1LMNAALDH1A1 | |
| SCHEMBL9233976 | 0.76 | DHFR (0.56) | ARMAPTTHRBLMNAALDH1A1 | |
| SCHEMBL1892647 | 0.76 | IL4I1 (0.51) | THRBL3MBTL1POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685467-A1 | NOVEL PYRIMIDINE DERIVATIVE AND MEDICINAL COMPOSITION | NKK CORPORATION (JP) | 1995-12-06 | — | — | EP | disclosed |