SCHEMBL5345117

SCHEMBL5345117

CCC1(C)c2ccccc2N(C)C12C=Nc1c(ccc3ccc(OC)cc13)O2

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.79
THRB P10828 5/20 0.79
KDM4E B2RXH2 5/20 0.79
SMN1; SMN2 Q16637 4/20 0.79
LMNA P02545 4/20 0.79
GAA P10253 4/20 0.79
RECQL P46063 3/20 0.79
TDP1 Q9NUW8 3/20 0.79
ALDH1A1 P00352 2/20 0.79
HPGD P15428 2/20 0.79
HTT P42858 2/20 0.79
ALOX12 P18054 2/20 0.79
L3MBTL1 Q9Y468 2/20 0.79
MAPK1 P28482 2/20 0.79
POLB P06746 2/20 0.79
PKM P14618 2/20 0.58
NPSR1 Q6W5P4 4/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620516 0.88 MAPT (1.00) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL9061827 0.87 MAPT (0.76) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL9868518 0.83 MAPT (0.60) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL9061121 0.82 MAPT (0.59) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL9230491 0.82 MAPT (0.52) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL9996010 0.80 MAPT (0.80) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL4621970 0.79 MAPT (0.79) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL13809185 0.79 MAPT (0.75) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL9912585 0.78 MAPT (0.74) MAPTTHRBKDM4ESMN1; SMN2LMNA
SCHEMBL13578501 0.78 MAPT (0.74) MAPTTHRBKDM4ESMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11359136-B2 Colorimetric indicators for photocurable sealants THE BOEING COMPANY (US) 2022-06-14 US claimed
EP-4077464-B1 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC DESOTO INT INC (US) 2026-04-29 EP disclosed
US-12559593-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (CA) 2026-02-24 US disclosed
US-20240199911-A1 HYBRID DUAL CURE COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-06-20 US disclosed
US-20240132752-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-DESOTO INTERNATIONAL, INC. (US) 2024-04-25 US disclosed
EP-4314115-A1 HYBRID DUAL CURE COMPOSITIONS PRC-Desoto International, Inc. (US) 2024-02-07 EP disclosed
EP-4294856-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-Desoto International, Inc. (US) 2023-12-27 EP disclosed
CN-117043234-A Composition containing radical polymerization initiator PRC-迪索托国际公司 2023-11-10 CN disclosed
US-20230242710-A1 Dual Cure Sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2023-08-03 US disclosed
US-11655340-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2023-05-23 US disclosed
US-20210187922-A1 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC-DESOTO INTERNATIONAL, INC. (US) 2021-06-24 US disclosed
US-20210189206-A1 ADHESION-PROMOTING INTERLAYER COMPOSITIONS CONTAINING ORGANIC TITANATES/ZIRCONATES AND METHODS OF USE PRC-DESOTO INTERNATIONAL, INC. 2021-06-24 US disclosed
WO-2021127292-A2 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC-DESOTO INTERNATIONAL, INC. (US) 2021-06-24 WO disclosed
WO-2020264115-A1 METHODS FOR MANUFACTURING WIND TURBINE BLADES AND LEADING EDGE PROTECTION SURFACES PPG COATINGS EUROPE B.V. (NL) 2020-12-30 WO disclosed
US-20200199300-A1 Dual Cure Sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2020-06-25 US disclosed
US-20170292068-A1 Colorimetric Indicators for Photocurable Sealants THE BOEING COMPANY 2017-10-12 US disclosed
US-20070261273-A1 Shoe having photoreactive components CHEUNG JAMES 2007-11-15 US disclosed
US-20030074808-A1 Article of footwear containing a photoreactive composition ELAN-POLO, INC. 2003-04-24 US disclosed
US-20020022008-A1 UV indicator to signal the reduction of sunscreen efficiency PROCTER & GAMBLE COMPANY, THE 2002-02-21 US disclosed
US-5581090-A SOLAR RADIATION-SENSITIVE ELEMENTS HAVING COATINGS CONTAINING DERIVATIVES OF SPIROXAZINES OR SPIROPYRANS, ALSO MOLDINGS HAVING THOSE COMPOUNDS MIXED INTO TRANSPARENT PLASTICS SOLARTECH ENTERPRISES, LLC (US) 1996-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020022008-A1 UV indicator to signal the reduction of sunscreen efficiency SUN2, ERCC2, ERCC5 MAPT 2917/4885THRB 4436/4885KDM4E 3671/4885
US-12559593-B2 Dual cure sealants DUOX2, DUOX1, GPX4 MAPT 2965/4885THRB 2985/4885KDM4E 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.