Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.42 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231659 | 0.93 | LTC4S (0.46) | HSD11B1TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL27486585 | 0.85 | KAT6A (0.47) | HSD11B1TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL1773416 | 0.85 | RAB9A (0.56) | HSD11B1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9229708 | 0.84 | LTC4S (0.48) | HSD11B1TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL9230984 | 0.84 | LTC4S (0.53) | HSD11B1TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL14415761 | 0.81 | CES2 (0.53) | NPC1RAB9ABRAFSMN1; SMN2 | |
| SCHEMBL690501 | 0.80 | KAT6A (0.54) | HSD11B1TAS1R3TAS1R1TAS1R2KAT6A | |
| SCHEMBL1773728 | 0.80 | CES2 (0.53) | RAB9ABRAF | |
| SCHEMBL27437820 | 0.78 | LTC4S (0.43) | HSD11B1KAT6ALTC4SF10GPR139 | |
| SCHEMBL14297682 | 0.77 | ELANE (0.49) | TAS1R3TAS1R1TAS1R2KAT6AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | disclosed |