Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228226 | 0.86 | TAAR1 (0.51) | TAAR1ABCB1HTR1ACYP2C19DRD2 | |
| SCHEMBL9231960 | 0.79 | ALOX5 (0.45) | TAAR1 | |
| SCHEMBL9231953 | 0.79 | ALOX5 (0.45) | TAAR1 | |
| SCHEMBL9229299 | 0.75 | TAAR1 (0.51) | TAAR1ABCB1HTR1ACYP2C19DRD2 | |
| SCHEMBL9230011 | 0.74 | TAAR1 (0.54) | TAAR1ABCB1HTR1ACYP2C19DRD2 | |
| SCHEMBL16664938 | 0.72 | TAAR1 (0.42) | TAAR1CYP2C19L3MBTL1CYP2D6IDO1 | |
| SCHEMBL9231905 | 0.72 | TAAR1 (0.48) | TAAR1ABCB1HTR1ACYP2C19DRD2 | |
| SCHEMBL27871550 | 0.71 | TAAR1 (0.54) | TAAR1MEN1KMT2ABCHEMAOB | |
| SCHEMBL27884091 | 0.70 | TAAR1 (0.53) | TAAR1MEN1KMT2AIDO1AGXT | |
| SCHEMBL7450409 | 0.70 | TAAR1 (0.70) | TAAR1IDO1AGXTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |