Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916171 | 0.85 | SGMS2 (0.49) | CYP1A2CYP2C9CYP2C19L3MBTL1IDO1 | |
| SCHEMBL27919782 | 0.80 | ALDH1A1 (0.40) | CYP1A2CYP2C9CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL1442239 | 0.77 | TAAR1 (0.62) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL620934 | 0.77 | CASR (0.52) | TAAR1KMT2ASGMS2MAOB | |
| SCHEMBL9230601 | 0.75 | TAAR1 (0.51) | TAAR1ABCB1KMT2AHTR1ADRD2 | |
| SCHEMBL9228226 | 0.75 | TAAR1 (0.51) | TAAR1ABCB1KMT2AHTR1ADRD2 | |
| SCHEMBL8417617 | 0.75 | TAAR1 (0.58) | TAAR1CYP1A2IDO1AGXT | |
| SCHEMBL623518 | 0.74 | KMT2A (0.43) | TAAR1KMT2AHTR1AL3MBTL1ALDH1A1 | |
| SCHEMBL9230011 | 0.74 | TAAR1 (0.54) | TAAR1ABCB1KMT2AHTR1ADRD2 | |
| SCHEMBL7872355 | 0.74 | ABCB1 (0.54) | ABCB1HTR1ADRD2ALDH1A1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |