Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991514 | 0.87 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1472176 | 0.82 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL5815970 | 0.80 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL2918735 | 0.79 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL11344728 | 0.78 | SMN1; SMN2 (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1470739 | 0.78 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4359009 | 0.77 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10352079 | 0.77 | SMN1; SMN2 (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9230603 | 0.77 | SMN1; SMN2 (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27658426 | 0.77 | SMN1; SMN2 (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661298-A2 | Diene polymers and copolymers having an alkoxysilane group | BRIDGESTONE CORPORATION (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-4276135-A | Photocurable organopolysiloxane compositions | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 1981-06-30 | — | — | US | disclosed |