Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726087 | 0.87 | KMO (0.56) | KMOALDH1A1TSHRHDAC8RXRA | |
| SCHEMBL699008 | 0.85 | KMO (0.67) | KMOALDH1A1TSHRHDAC8RXRA | |
| SCHEMBL30698052 | 0.85 | KMO (0.67) | KMOALDH1A1TSHRHDAC8RXRA | |
| SCHEMBL28032601 | 0.85 | KMO (0.59) | KMOALDH1A1TSHRHDAC8RXRA | |
| Hydrogen Sulfide SCHEMBL27896825 | 0.83 | KMO (0.64) | KMOALDH1A1TSHRHDAC8RXRA | |
| SCHEMBL7067814 | 0.83 | SCN9A (0.50) | — | |
| SCHEMBL2213546 | 0.81 | KMO (0.73) | KMOTSHRPTGER1RXRARXRB | |
| SCHEMBL30259065 | 0.81 | KMO (0.73) | KMOTSHRPTGER1RXRARXRB | |
| SCHEMBL27510 | 0.79 | ALDH1A1 (0.59) | KMOALDH1A1TSHRHDAC8ATM | |
| SCHEMBL1707626 | 0.79 | KMO (0.70) | KMOTSHRPTGER1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393612-A | Conductor and insulating coating having tensile strength of at least 13 kg/mm2 | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1995-02-28 | — | — | US | disclosed |