Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234357 | 0.98 | SMN1; SMN2 (0.32) | SMN1; SMN2S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL9232214 | 0.98 | LMNA (0.36) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL9235101 | 0.98 | LMNA (0.36) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL9235842 | 0.96 | LMNA (0.34) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL9234676 | 0.96 | S1PR1 (0.31) | SMN1; SMN2S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL9237488 | 0.94 | TNNC1 (0.33) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL9236932 | 0.94 | ALDH1A1 (0.31) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL9235445 | 0.92 | S1PR1 (0.31) | SMN1; SMN2S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL9237350 | 0.90 | TNNC1 (0.33) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL9236179 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464889-A | Stabilization of thermoplastic resins | GENERAL ELECTRIC COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0635512-A1 | Cyclic phosphites as polymer stabilizers | GENERAL ELECTRIC COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |