Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227997 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL929137 | 0.84 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL9230355 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL9225471 | 0.79 | POLB (0.40) | ALDH1A1MAOASMN1; SMN2LMNAMAOB | |
| SCHEMBL27410808 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL13533050 | 0.76 | KDM4E (0.59) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL15628873 | 0.75 | KDM4E (0.64) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL13534194 | 0.74 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL7803728 | 0.73 | KDM4E (0.62) | ALDH1A1KDM4EHSD17B10HPGDMAOA | |
| SCHEMBL929374 | 0.73 | KDM4E (0.62) | ALDH1A1KDM4EHSD17B10HPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650964-A1 | 1 2H-1-benzopyran-2-one-8-yl -piperazine derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1995-05-03 | — | — | EP | disclosed |