Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227997 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10MAOALMNA | |
| SCHEMBL9230906 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10MAOALMNA | |
| SCHEMBL929137 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10MAOALMNA | |
| SCHEMBL9226994 | 0.79 | CA9 (0.38) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27410808 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10MAOALMNA | |
| SCHEMBL15628873 | 0.72 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MAOALMNA | |
| Hydrochloric Acid SCHEMBL9228397 | 0.72 | DRD2 (0.53) | MAPTBACE1 | |
| SCHEMBL10514375 | 0.71 | HTR1A (0.57) | — | |
| SCHEMBL27436549 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10MAOALMNA | |
| SCHEMBL13534194 | 0.71 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10MAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650964-A1 | 1 2H-1-benzopyran-2-one-8-yl -piperazine derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1995-05-03 | — | — | EP | disclosed |