Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119359 | 0.88 | KMT2A (0.65) | OPRK1PDE4DKMT2AMEN1MAPT | |
| SCHEMBL9565728 | 0.83 | OPRK1 (0.55) | OPRK1PDE4DKMT2AMEN1MAPT | |
| SCHEMBL11656315 | 0.82 | KMT2A (0.53) | OPRK1PDE4DKMT2AMEN1MAPT | |
| SCHEMBL5437358 | 0.81 | OPRK1 (0.56) | OPRK1PDE4DKMT2AMEN1MAPT | |
| SCHEMBL15837517 | 0.80 | MEN1 (0.62) | KMT2AMEN1ALDH1A1TSHRHTT | |
| SCHEMBL11650436 | 0.80 | KMT2A (0.52) | OPRK1PDE4DKMT2AMEN1MAPT | |
| SCHEMBL10508406 | 0.79 | KMT2A (0.55) | KMT2AMEN1MAPTCASP6GAA | |
| SCHEMBL11653799 | 0.78 | HPN (0.56) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL9819370 | 0.76 | KMT2A (0.53) | KMT2AMEN1MAPTCASP6GAA | |
| SCHEMBL11655036 | 0.75 | OPRK1 (0.55) | OPRK1PDE4DKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-4399280-A | MOTHPROOFING, PROTECTION OF KERATINOUS MATERIAL | CIBA-GEIGY CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4283444-A | MOTHPROOFING WOOLS, FURS, SKINS | CIBA-GEIGY CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4259488-A | Bis-isoindoline pigments | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4062836-A | YELLOW | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |