Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123624 | 0.88 | MEN1 (0.61) | OPRK1PDE4DMEN1KMT2AELANE | |
| SCHEMBL5443754 | 0.83 | ELANE (0.57) | OPRK1PDE4DMEN1KMT2AELANE | |
| SCHEMBL5437358 | 0.83 | OPRK1 (0.56) | OPRK1PDE4DMEN1KMT2AMGLL | |
| SCHEMBL9230907 | 0.83 | OPRK1 (0.57) | OPRK1PDE4DMEN1KMT2AMGLL | |
| SCHEMBL9565725 | 0.81 | MEN1 (0.49) | OPRK1PDE4DMEN1KMT2AMGLL | |
| SCHEMBL11785882 | 0.81 | MAPT (0.44) | OPRK1PDE4DMEN1KMT2AELANE | |
| SCHEMBL11656315 | 0.81 | KMT2A (0.53) | OPRK1PDE4DMEN1KMT2AALDH1A1 | |
| SCHEMBL11745569 | 0.79 | MGLL (0.53) | OPRK1PDE4DMEN1KMT2AMGLL | |
| SCHEMBL11160362 | 0.78 | MEN1 (0.44) | OPRK1PDE4DMEN1KMT2AELANE | |
| SCHEMBL10858522 | 0.78 | ELANE (0.47) | MEN1KMT2AELANEMGLLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4399280-A | MOTHPROOFING, PROTECTION OF KERATINOUS MATERIAL | CIBA-GEIGY CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4283444-A | MOTHPROOFING WOOLS, FURS, SKINS | CIBA-GEIGY CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4097475-A | FOR POLYESTERS AND BLENDS WITH CELLULOSE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-27 | — | — | US | disclosed |