Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958050 | 0.87 | GPR55 (0.50) | CYP3A4CYP2D6TSHRCYP2C19GPR55 | |
| SCHEMBL8018566 | 0.84 | PTGER1 (0.58) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL2628164 | 0.82 | PTGER1 (0.43) | CYP3A4CYP2D6TSHRCYP2C19GPR55 | |
| SCHEMBL30024107 | 0.80 | DRD1 (0.48) | CYP3A4TSHRCYP2C19GPR55PTGER1 | |
| SCHEMBL28870072 | 0.80 | SLC6A9 (0.49) | CYP3A4CYP2D6TSHRCYP2C19PTGER1 | |
| SCHEMBL4442750 | 0.80 | BCL2 (0.54) | CYP3A4CYP2D6TSHRCYP2C19BCL2 | |
| SCHEMBL1332146 | 0.79 | PTGDR2 (0.61) | BCL2L1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28870119 | 0.79 | PTGER1 (0.44) | CYP3A4CYP2D6TSHRCYP2C19GPR55 | |
| SCHEMBL28870165 | 0.79 | CYP3A4 (0.42) | CYP3A4CYP2D6TSHRCYP2C19GPR55 | |
| SCHEMBL19251013 | 0.79 | ALDH1A1 (0.47) | CYP3A4CYP2D6TSHRCYP2C19PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664316-A1 | Polycarbonate composition having improved resistance to gamma-ray radiation | TEIJIN LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-4200717-A | Preparation of propylene polymer-containing solid titanium trichloride and propylene polymers using same | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1980-04-29 | — | — | US | disclosed |
| US-4115533-A | REDUCING TITANIUM TETRACHLORIDE WITH AN ORGANIC ALUMINUM COMPOUND | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
| US-4115532-A | LEWIS ACIDS, HEATING, PRECIPITATION | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
| US-4060593-A | Preparation of titanium trichloride | MITSUBISHI CHEMICAL INDUSTRIES (JA) | 1977-11-29 | — | — | US | disclosed |