Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234818 | 0.92 | LMNA (0.52) | POLBLMNATP53MAPT | |
| SCHEMBL9229586 | 0.92 | LMNA (0.53) | POLBLMNAMAPT | |
| SCHEMBL9235150 | 0.91 | PLOD2 (0.41) | HSD17B10POLBLMNATP53 | |
| SCHEMBL9228543 | 0.90 | RXFP1 (0.52) | POLBLMNATP53MAPT | |
| SCHEMBL9233408 | 0.90 | LMNA (0.46) | POLBLMNATP53MAPT | |
| SCHEMBL9235618 | 0.90 | IDO1 (0.47) | LMNATP53MAPT | |
| SCHEMBL8669435 | 0.89 | HSD17B10 (0.54) | HSD17B10POLBLMNA | |
| SCHEMBL9231790 | 0.86 | LMNA (0.45) | HSD17B10POLBLMNATP53MAPT | |
| SCHEMBL9234495 | 0.86 | LMNA (0.48) | HSD17B10POLBLMNATP53MAPT | |
| SCHEMBL9228514 | 0.85 | POLB (0.47) | HSD17B10POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541182-A | Benzodiazepine aryl urea derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0591529-A1 | NOVEL BENZODIAZEPINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |