Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231790 | 0.88 | LMNA (0.45) | LMNAPOLBHSD17B10TP53MAPT | |
| SCHEMBL9233268 | 0.87 | LMNA (0.43) | LMNAPOLBTP53 | |
| SCHEMBL9232260 | 0.86 | HSD17B10 (0.45) | LMNAPOLBHSD17B10TP53MAPT | |
| SCHEMBL9229586 | 0.85 | LMNA (0.53) | LMNAPOLBMAPT | |
| SCHEMBL8669435 | 0.84 | HSD17B10 (0.54) | LMNAPOLBHSD17B10 | |
| SCHEMBL9234481 | 0.84 | LMNA (0.43) | LMNAPOLBHSD17B10TP53MAPT | |
| SCHEMBL9233408 | 0.83 | LMNA (0.46) | LMNAPOLBTP53MAPT | |
| SCHEMBL9234338 | 0.83 | CBX7 (0.51) | LMNAPOLBMAPT | |
| SCHEMBL9573425 | 0.82 | SMN1; SMN2 (0.46) | LMNAPOLBHSD17B10TP53MAPT | |
| SCHEMBL9573568 | 0.81 | SMN1; SMN2 (0.44) | LMNAPOLBHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541182-A | Benzodiazepine aryl urea derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0647632-A1 | NOVEL BENZODIAZEPINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-04-12 | — | — | EP | disclosed |
| EP-0591529-A1 | NOVEL BENZODIAZEPINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |