Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30265456 | 0.86 | KDM4E (0.41) | MDM4ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL309235 | 0.73 | TDP1 (0.41) | KDM4EALDH1A1CYP1A2ERBB2FYN | |
| SCHEMBL28671989 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1CYP1A2ERBB2FYN | |
| SCHEMBL22703043 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1CYP1A2ERBB2FYN | |
| SCHEMBL25017521 | 0.71 | ESR1 (0.51) | ESR1ESR2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL16929708 | 0.69 | CYP1A2 (0.47) | KDM4EALDH1A1CYP1A2ERBB2FYN | |
| SCHEMBL4412391 | 0.68 | ALDH1A1 (0.47) | KDM4EALDH1A1CYP1A2MEN1GAA | |
| SCHEMBL27402 | 0.68 | CYP1A2 (0.44) | KDM4EALDH1A1CYP1A2ERBB2FYN | |
| SCHEMBL5470770 | 0.68 | CYP1A2 (0.44) | KDM4EALDH1A1CYP1A2ERBB2FYN | |
| SCHEMBL29354165 | 0.68 | CYP1A2 (0.44) | KDM4EALDH1A1CYP1A2ERBB2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640562-A2 | Spheres, process for their preparation and uses | Oeste, Franz-Dietrich (DE) | 1995-03-01 | — | — | EP | disclosed |