SCHEMBL309235

SCHEMBL309235

N#Cc1c(C#N)c2ccc3cccc4cc(C#N)c(c1C#N)c2c34

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ CYP1A2 P05177 2/20 0.40
▸ ERBB2 P04626 1/20 0.40
▸ FYN P06241 1/20 0.40
▸ MAOA P21397 1/20 0.40
▸ ACHE P22303 1/20 0.40
▸ AHR P35869 1/20 0.40
▸ DYRK1A Q13627 3/20 0.38
▸ CLK1 P49759 2/20 0.38
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ CYP1A1 P04798 2/20 0.37
▸ CYP1B1 Q16678 2/20 0.37
▸ HTT P42858 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ TSHR P16473 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16929708 0.85 CYP1A2 (0.47) TDP1KDM4ECYP1A2ERBB2FYN
SCHEMBL28671989 0.77 ALDH1A1 (0.43) TDP1KDM4ECYP1A2ERBB2FYN
SCHEMBL29820672 0.75 CA1 (0.39) KDM4ECYP1A2ERBB2FYNMAOA
SCHEMBL28948920 0.74 PGR (0.33) KDM4EHTTALDH1A1ANPEP
SCHEMBL5748495 0.73 CYP1A2 (0.46) TDP1KDM4ECYP1A2ERBB2FYN
SCHEMBL5750983 0.73 CYP1A2 (0.46) TDP1KDM4ECYP1A2ERBB2FYN
SCHEMBL9232387 0.73 MDM4 (0.38) TDP1KDM4ECYP1A2ERBB2FYN
Hydrazine SCHEMBL28831253 0.72 CA1 (0.36) KDM4ECYP1A2ERBB2FYNMAOA
SCHEMBL4412391 0.72 ALDH1A1 (0.47) TDP1KDM4ECYP1A2CA1CA2
SCHEMBL5749081 0.71 KDM4E (0.44) TDP1KDM4ECYP1A2ERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10281831-B2 Imaging members comprising capped structured organic film compositions XEROX CORPORATION (US) 2019-05-07 — — US claimed
US-20160259256-A1 IMAGING MEMBERS COMPRISING CAPPED STRUCTURED ORGANIC FILM COMPOSITIONS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2016-09-08 — — US claimed
EP-1081164-B1 Binder resin with reduced hydroxyl content XEROX CORP (US) 2015-04-01 — — EP claimed
US-8097387-B2 Photoreceptors comprising aligned nano-sized domains of charge transport components that have significant intermolecular pi-pi orbital overlap XEROX CORPORATION (US) 2012-01-17 — — US claimed
US-20090226829-A1 PHOTORECEPTORS COMPRISING ALIGNED NANO-SIZED DOMAINS OF CHARGE TRANSPORT COMPONENTS THAT HAVE SIGNIFICANT INTERMOLECULAR PI-PI ORBITAL OVERLAP XEROX CORPORATION (US) 2009-09-10 — — US claimed
EP-0017513-B2 ELECTROPHOTOGRAPHIC MEMBER AND PROCESS FOR FORMING A LATENT IMAGE RANK XEROX LIMITED (GB) 1986-12-30 — — EP claimed
US-4407918-A Electrophotographic process and apparatus for making plural copies from a single image OLYMPUS OPTICAL COMPANY LIMITED (JP) 1983-10-04 — — US claimed
EP-0017513-B1 ELECTROPHOTOGRAPHIC MEMBER AND PROCESS FOR FORMING A LATENT IMAGE RANK XEROX LIMITED (GB) 1983-01-19 — — EP claimed
US-4315980-A ELECTRON ACCEPTOR ACTIVATORS FUJI XEROX CO., LTD. (JP) 1982-02-16 — — US claimed
US-4277551-A PHOTOCONDUCTIVE LAYER OF SELENIUM AND TELLURIUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-07-07 — — US claimed
EP-0017513-A1 Electrophotographic member and process for forming a latent image RANK XEROX LIMITED (GB) 1980-10-15 — — EP claimed
US-4161404-A Photosensitive material for use in electrophotography with a poly alkyl or benzyl glutamate RICOH CO., LTD. (JP) 1979-07-17 — — US claimed
US-3956524-A Method for the preparation of electrostatographic photoreceptors XEROX CORPORATION (US) 1976-05-11 — — US claimed
US-20250015309-A1 ELECTROCHEMICAL HYDROGEN-CATALYST POWER SYSTEM BRILLIANT LIGHT POWER, INC. (US) 2025-01-09 — — US disclosed
US-11918951-B2 MOF compositions for selective separation of hydrocarbons RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-03-05 — — US disclosed
US-20210339186-A1 MOF COMPOSITIONS FOR SELECTIVE SEPARATION OF HYDROCARBONS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2021-11-04 — — US disclosed
US-4047948-A Composite layered imaging member for electrophotography XEROX CORPORATION (US) 1977-09-13 — — US disclosed
US-4030923-A Mixture of binder materials for use in connection with a charge transport layer in a photoconductor INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1977-06-21 — — US disclosed
US-3956524-A Method for the preparation of electrostatographic photoreceptors XEROX CORPORATION (US) 1976-05-11 — — US disclosed
US-3953207-A Composite layered photoreceptor XEROX CORPORATION (US) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210339186-A1 MOF COMPOSITIONS FOR SELECTIVE SEPARATION OF HYDROCARBONS EPCAM, TPR, TNFSF10 TDP1 3214/4885KDM4E 1301/4885CYP1A2 4254/4885
US-11918951-B2 MOF compositions for selective separation of hydrocarbons EPCAM, TPR, TNFSF10 TDP1 3214/4885KDM4E 1301/4885CYP1A2 4254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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